Follicular helper T (Tfh) cells are one of CD4+ helper T subsets which promote B cell maturation, activation and antigen-specific Draught Excluder antibody production.Autoantibodies are hallmarks of autoimmune diseases, and crucial contributions of Tfh cells in development of these diseases are now evident.Deregulation of Tfh activities can contrib
Alcohol-related liver disease (ALD) is recognized as a global health crisis, contributing to approximately 20% of liver cancer-associated fatalities.Dysbiosis of the gut microbiome is associated with the development of ALD, with the gut microbial metabolite urolithin A (UA) exhibiting a potential for alleviating liver symptoms.However, the protecti
Abstract Background Numerous studies have shown that Epstein-Barr virus (EBV) and cytomegalovirus (CMV) can infect immunocompetent patients simultaneously with other agents.Nonetheless, multiple infections with other agents in EBV/CMV-infected children have received little attention.We conducted a retrospective study of children with suspected infe
In neurosurgery intensive care units, cerebrovascular reactivity tests for neuromonitoring are used to evaluate the status of cerebral blood flow autoregulation; lack of autoregulation indicates a poor SIDEBOARD patient outcome.The goal of neuromonitoring is to prevent secondary injuries following a primary central nervous system injury, when the b